Modern biotechnology can bring many benefits, but there are concerns that it could also have adverse impacts on biodiversity and human health. It concludes that urgent action is needed now to avoid significant costs of inaction, both in economic and human terms. Indiana university is actively committed to preserving the health and safety of its students, staff, and faculty, and to protecting the environment and the community. An anticipatory governance challenge use of the techniques of modern biotechnology in agriculture and food production has given rise to impassioned debates over the last two decades. The high efficiency particolate air hepa filter and the development of biological containment devices. The university policies listed below have been approved by the senate andor the board of trustees and can be accessed from the website of the queens university secretariat and legal counsel. Biosafety for human health and the environment in the context of the potential use of genetically modified mosquitoes. Biosafety consulting environmental health engineering. Biosafety enables laboratories to conduct accurate and timely patient diagnostic tests without jeopardizing the health of their workers, the environment, or the public.
University of toledo environmental health and radiation safety. Department of health and human services centers for disease control and prevention morbidity and mortality weekly report guidelines for biosafety. Such materials would include, but are not limited to. Centers for disease control and prevention national institutes of health hhs publication no.
Oecd work on chemical safety and biosafety by the mid1970s, however, it became clear that concentrating on a few chemicals at a time would not be enough to protect human health and the environment. Principles and concepts of biosafety environmental health. Footnote 5 it is a guidance document for canadian facilities where human and terrestrial animal pathogens are handled, that updates the guidelines originally published as part ii of the. Work with unfixed human tissues requires the use of universal precautions and biosafety level 2. Summarising the various aspects of biological safety in biotechnology is a matter of. Policies and standard operating procedures sops queens university policies and terms of reference. Services, national institutes of health, department of health and human serv ices, washington. The biosafety environmental release regulations, 2011. Canadian biosafety standard cbs second edition canada. Biosecurity hazards10 of various types exist in each sector and have high potential to move between sectors e. Biosafety is a wellestablished concept with a widelyaccepted meaning and international guidance on how it is put into practice at the national level.
Cleb is comprised of subject matter experts, an animal health expert, and an occupational physician, as well as community members. Biosafety in microbiological and biomedical laboratories. Tdr biosafety for human health and the environment in. The biological safety program is responsible for providing support to the university of texas health science center at houston students and personnel concerning the recognition, evaluation, and control of chemical, biological, and physical hazards. A known risk will lead to the implementation of appropriate prevention measures. Biosafety levels bsl o bsl1 o bsl2 o bsl3 bsl3ag o bsl4. The world health organization who has long recognized that safety and, in particular, biological safety are important international issues. A pathogen that can cause disease in humans or animals but is unlikely to be a serious hazard. Selection, installation and use of biological safety cabinets introduction. The following terminologies associated with biological risks are defined or described. Biosafety, in medicine and health care settings, specifically refers to proper handling of organs or tissues from biological origin, or genetic therapy products, viruses with respect to the environment, to ensure the safety of health care workers, researchers, lab staff, patients, and the general public. We want to stress the importance of working safely and responsibly with biological and. Concepts of biosafety and biosecurity deal with related but distinctly different issues. Biosafety in microbiology and biomedical laboratories,u.
The cartagena protocol on biosafety, a supplement to the convention on biological diversity, aims to ensure the safe handling, transport and use of organisms that have been modified using modern biotechnology. Biological safety training njit environmental health and safety department will ensure that all laboratory staff, students, as well as investigators, who may potentially come into contact with biological materials in the laboratory attend a yearly biological safety training session. Biosafety in biotechnology encyclopedia of life support. Good biological safety practices protect the environment from release of potentially harmful agents. All individuals are required to file a registration with the office of prospective health biological safety, if they wish to work with a covered biohazard biotoxins, allergens, biohazardous agents, microorganisms with an assigned biosafety level 2 or higher, human tissues, body fluids and commercially available human cell lines, any. State laboratory of public health is to plan, develop, and train policies and procedures which ensure a robust biosafety environment in public health and sentinel laboratories throughout north carolina. Guidelines for research involving recombinant or synthetic nucleic acid molecules pdf 1. Biosafety for human health and the environment in the context.
Department of health and human services, hhs publication cdc 998395. Laboratory biosafety manual world health organization. One important biosafety element suggested for all 4 biosafety levels is biosafety training. Biosafety introduction to the queens biosafety program and manual. Biosafety manual university of washington, environmental health. Researchers and other personnel who work with human and nonhuman primates fluids, tissues or cells including cell lines are required to take bloodborne pathogen training oh 218 anually and be offered hepatitis b vaccination free of charge by the university. Research ethic and complianceinstitutional biosafety committee ibc. Biosafety practices are used in the proper handling of biohazardous organisms.
Modern biotechnology has both positive and negative implications for human health, the environment, and trade. If a needle must be recapped, using a needle holder to do so. We develop biosafety programs and training that minimize the risks of exposure and ensure compliance with the guidelines for biosafety from the centers for disease control and prevention cdc and the national institutes of health nih as well as a variety of local, state and federal biosafety related regulations. Biohazardous organisms are microorganisms with an infectious potential for man, animals and plants in the environment. The committee for laboratory and environmental biosafety cleb serves as uc berkeleys institutional biosafety committee ibc. Ofice of environment, health safety 3 return to table of contents introduction to cleb the committee for laboratory and environmental biosafety cleb serves as uc berkeleys institutional biosafety committee ibc. In this booklet you will find all the information that was already present in the earlier editions. Cdc and the association of public health laboratories. The canadian biosafety handbook cbh, 2 nd edition, 2016 is intended as a companion document to the canadian biosafety standard cbs, 2 nd edition, 2015. A microorganism that is unlikely to cause human or animal disease. We work hard so that the campus and your work environment are as safe as possible, to protect you from harm and to prevent accidents and injuries. Biosafety in microbiological and biomedical laboratories cdc. These generally have a single sector perspective e. The intent of the biosafety program at queens university, and the purpose of the queens biosafety manual, is to guide personnel in how to work safely with biological material that can be hazardous to people andor animals.
The government of canadas canadian biosafety standard cbs, 2 nd edition, 2015, is a harmonized national standard for the handling or storing of human and terrestrial animal pathogens and toxins in canada. Biosafety for human health and the environment in the context of the potential use of genetically modified mosquitoes gmms pdf 2. Biosafety, in medicine and health care settings, specifically refers to proper handling of organs or tissues from biological origin, or genetic therapy products, viruses with respect to the environment, to ensure the safety of health care workers. Cleb is comprised of subject matter experts, an animal health expert, an occupational physician, as well as community members. This is the third, revised edition of the booklet biosafety in the laboratory. Canadian biosafety handbook, second edition canada. Effective treatment and preventive measures are available and the.
Biosafety for human health and the environment in the. Assessment of biological risks belgian biosafety server. Uw affiliated clinical investigators doing research with recdna in human. It is through their absolute commitment to quality, technical accuracy, and dedication to the professional. Print the full version of biosafety in microbiological and biomedical laboratories bmbl 5th edition pdf 4 mb bmbl foreword biosafety in microbiological and biomedical laboratories bmbl quickly became the cornerstone of biosafety practice and policy in the united states upon first publication in 1984. Tdr biosafety for human health and the environment in the. This manual is based on a series of biosafety courses on genetically modified mosquitoes that were held in africa, asia and latin america during 20082011. Several attempts have been made to classify human, animal and plant pathogens according to the risks they present to the laboratory staff first, and next to the. Only a few alterations have been made, especially in the text concerning decontamination and inactivation. Designed to protect human health and prevent release of pathogens into the environment. Principles and concepts of biosafety environmental.
We hope you find this 5th edition of biosafety in microbiological and. Biological safety manual environment, health and safety. Comply with applicable federal, state, and local requirements. We support governments to manage the potential adverse effects and benefits of modern biotechnology, with a focus on protecting biological diversity and human health. Atlanta, ga 30333 adapted from the cdcnih 3rd edition of biosafety in microbiological and biomedical laboratories introduction from the earliest days of microbiological research, laboratorians have recognized that.
Researchers and other personnel who work with human and nonhuman. Policies and standard operating procedures environmental. Sarscov2 biosafety guideline pdf link to ehs sarscov2 information page. Cdc nih biosafety in microbiological and biomedical laboratories bmbl. Cartagena protocol on biosafety9, and the international health regulations. Oecd work on chemical safety and biosafety the oecd environment directorate helps countries design environmental policies that are both economically effi cient and eff ective at achieving their. Provide an environment for quality research while maintaining a safe workplace. Biosafety resource book food and agriculture organization of the. Department of health and human services, 2009, the steps of the risk assessment process include. Concepts of biosafety and biosecurity deal with related but distinctly different. Canadian biosafety standards and guidelines canada. Contact ohp for information on the hepatitis b vaccination.
Biological safety program biological safety uthealth. Human, animal and plant life and health and protection of the environment are inextricably linked and this is the fundamental rationale for an integrated approach to biosecurity at the national level. Human, animal and plant materials may harbor biohazardous organisms or agents and such materials must be handled accordingly. Historically, the information in this publication has been advisory is nature even though legislation and regulation, in some circumstances, have overtaken it and made compliance with the guidance provided mandatory.
Welcome yale university is committed to health, safety and environmental protection in all of its programs and activities. The objective of a biosafety system is to prevent, manage, minimize or eliminate hazards to human health and security and to protect the environment from biological agents and organisms used in research and trade. An anticipatory governance challenge use of the techniques of modern biotechnology in agriculture and food production has given rise to impassioned debates over the last two decades about the benefits versus the risks posed by genetically modified organisms gmos and products thereof. Biosafety environmental health and safety dalhousie. Biotechnology can generate significant benefits, but there are concerns that it may have adverse impacts on biodiversity and human health. The risk assessment is performed to protect the human health and the environment from any adverse effect. It also helps maintain our academic excellence and integrity and ensure research funds from the national institutes of health nih and other funding sources. Biosafety in microbiological and biomedical laboratories bmbl quickly became the cornerstone of biosafety practice and policy in the united states upon first publication in 1984. Emorys environmental health and safety office ehso develops, implements and maintains programs aimed at protecting the safety and wellbeing of the campus community. Biological risk assessment is a process that includes the identification, the probability of occurrence and the severity of a potential adverse effect on human health or the environment associated with a specific use of a gmo or a pathogen. Development of protective policies and procedures to ensure safe environment when working with hazardous organisms o biocontaminants. Requirements for regulated laboratories and other containment zones handling human or animal pathogens and toxins. Biosafety in microbiological and biomedical laboratories utep. Robust laboratory biosafety is fundamental to an effective and efficient national response to an emerging infectious disease outbreak.
Biological safety helps protect the uw community of students, faculty, staff and visitors. Risk group 2 moderate individual risk, low community risk a pathogen that can cause human or animal disease but is unlikely to be a serious hazard to laboratory workers, the community, livestock or the environment. It is recognized that use of potentially pathogenic microorganisms, other biological materials, and organisms containing recombinant or synthetic nucleic acid molecules is. Bsl based on the risk they pose to human health and the environment. They have determined that biotech crops are as safe for human and animal health and for the environment as conventional crops. Biological material and living organisms are neither. With thousands of new chemical products entering the global market every year, oecd countries agreed that a more comprehensive strategy was needed. Although the implementation of these procedures is the.
At the same time, modern biotechnology is recognized as having a great potential for the promotion of human wellbeing, particularly in meeting critical needs for food, agriculture and health care. The goals of the biosafety program are to protect personnel from exposure to infectious agents, to prevent environmental contamination, to provide an environment for high quality research while maintaining a safe work place, and to comply with applicable federal, state and. Chair of the biological safety officers platform bvf platform. Canadian biosafety handbook 2 nd edition view the biosafety handbook on safe and secure handling of pathogens and toxins in canada. National biosafety authority biosafety regulations. This specialized agency of the united nations published the first.
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